Sodium starch glycolate is a white to off-white, odorless, tasteless powder. It consists of cross-linked carboxymethyl starch and exhibits high swelling properties upon contact with water, making it an effective tablet disintegrant.
Chemical Name and CAS Registry Number: Sodium carboxymethyl starch [9063-38-1]
Functional Category: Disintegrant
Used as a superdisintegrant in tablets and capsules at 2-8% concentration. It facilitates rapid drug release by promoting disintegration in aqueous environments.
Sodium starch glycolate is widely used due to its high swelling capacity and rapid disintegration properties. It is essential to optimize its concentration to prevent over-swelling, which may affect tablet integrity.
