Silicified Microcrystalline Cellulose (SMCC)
High-Performance Excipient for Enhanced Tableting Efficiency
Silicified Microcrystalline Cellulose (SMCC) is a co-processed excipient combining Microcrystalline Cellulose (MCC) with a small percentage of colloidal silicon dioxide (typically 2–5%). This synergistic blend enhances the physical and functional performance of MCC, making it a premium choice for direct compression and other high-speed tablet manufacturing processes.
Applications
Silicified Microcrystalline Cellulose (SMCC) is a co-processed excipient combining Microcrystalline Cellulose (MCC) with a small percentage of colloidal silicon dioxide (typically 2–5%). This synergistic blend enhances the physical and functional performance of MCC, making it a premium choice for direct compression and other high-speed tablet manufacturing processes.
Applications
- Direct compression tablets (ideal for poorly flowing APIs)
- Capsule filling
- Effervescent and chewable tablets
- High-speed rotary tablet presses
Chemical Name and CAS Registry Number : Cellulose [CAS: 9004-34-6]
Functional Category : Tablet and capsule diluent.
Specification
| Grade | LOD% | Bulk Density | Main Application |
|---|---|---|---|
| SMCC 50 | 3.0–5.0 | 0.27–0.35 | Fine standard SMCC grade with excellent flow and consolidation properties. Best disintegration time and superior binding performance. |
| SMCC 90 | 3.0–5.0 | 0.25–0.38 | Balanced flow and compaction properties. Ideal for high production speeds and rapid formulation development. |
| SMCC 90 HD | 3.0–5.0 | 0.35–0.50 | Higher bulk density and improved flow. Best suited for high-speed tableting and processing high-density actives with uniform tablet weight. |
FEATURES
Improved Flowability
The addition of silicon dioxide reduces inter-particulate friction, enhancing powder flow, critical for high-speed compression and uniform die filling.
Superior Compressibility
SMCC offers better binding properties and tablet hardness at lower compaction forces compared to standard MCC.
Versatile Functionality
Acts as a binder, filler, flow aid, and disintegrant in both pharmaceutical and nutraceutical tablet and capsule formulations.
Enhanced Blending Uniformity
Its improved flow and reduced segregation make SMCC ideal for formulations with low-dose APIs or poor flow actives.
