Microcrystalline Cellulose + Carboxymethylcelluloe Sodium (MCC + CMC-Na)
Microcrystalline Cellulose (MCC) + Carboxymethyl Cellulose Sodium (CMC-Na) is a multifunctional cellulose-based excipient blend offering excellent binding, thickening, and disintegration properties. It enhances tablet integrity, improves texture, and ensures consistent drug release without affecting bioavailability.
Applications:- Pharmaceuticals: Tablets, capsules, ODTs, suspensions
- Food & Beverages: Emulsifiers, stabilizers in sauces, dressings, dairy
- Cosmetics: Creams, lotions, gels, sunscreens
- Nutraceuticals: Herbal tablets, protein bars
- Personal Care: Hair care, skincare, and oral hygiene products
Chemical Name and CAS Registry Number : 9004-34-6 (Microcrystalline Cellulose), 9004-32-4 (Sodium Carboxymethyl Cellulose)
Functional Category : Stabilizing agent; suspending agent; tablet and capsule disintegrant; viscosity-increasing agent; water-absorbing agent.
Specification
| Grade | Viscosity (cps) | Assay (% CMC Na) | Particle Size Distribution | LOD (%) | Main Applications |
|---|---|---|---|---|---|
| MCC+CMC 581 | 70 – 170 (2.1% Solid) | 8.3 – 13.8 | 60# ≤ 0.1%, 200# ≤ 35%, 325# ≤ 8.0% | NMT 8.0 | Used in syrups, suspensions (antacid preparations, sprays, drenches, gels, emulsions). Also in dairy, beverages, bakery, sauces, dressings, and processed meat. |
| MCC+CMC 591 | 40 – 95 (1.2% Solid) | 8.3 – 13.8 | 60# ≤ 0.1%, 200# ≤ 45%, 325# ≤ 8.0% | NMT 8.0 | Similar to MCC+CMC 581, used in syrups, suspensions, and various food applications. |
| MCC+CMC 611 | 50 – 120 (2.6% Solid) | 11.3 – 18.8 | 60# ≤ 0.1%, 200# ≤ 50%, 325# ≤ 8.0% | NMT 8.0 | Used in syrups, suspensions, emulsions, and similar food products. |
FEATURES
Improved Flowability
The addition of silicon dioxide reduces inter-particulate friction, enhancing powder flow, critical for high-speed compression and uniform die filling.
Superior Compressibility
SMCC offers better binding properties and tablet hardness at lower compaction forces compared to standard MCC.
Versatile Function
Acts as a binder, filler, flow aid, and disintegrant in both pharmaceutical and nutraceutical tablet and capsule formulations.
Enhanced Blending Uniformity
Its improved flow and reduced segregation make SMCC ideal for formulations with low-dose APIs or poor flow actives.
