Pharmacopeial Specifications
-
Identification: Positive for manganese and stearate
-
Melting Point: 110–130°C
-
Loss on Drying: ≤3.0%
-
Solubility: Practically insoluble in water and organic solvents
-
Heavy Metals (as Mn): 5.0–10.0%
-
Residue on Ignition: ≤0.5%
Applications in Pharmaceutical Formulation
Manganese stearate is used as a lubricant and stabilizer in tablet manufacturing. It prevents sticking and improves tablet release properties. It is also employed in polymer and plastic formulations for drug packaging materials.
Comments
Although not as commonly used in pharmaceuticals as other stearates, manganese stearate offers specialized applications where metal-stearate interactions can be beneficial. However, its use should be carefully monitored due to potential concerns over manganese exposure.
