Pregelatinized Starch

Pharmacopeial Specifications:

• Identification: Complies with starch tests
• Loss on Drying: ≤14%
• pH (10% dispersion): 4.5–7.0
• Microbial Limits: Complies with pharmacopeial standards

Applications in Pharmaceutical Formulation:

Used as a multifunctional excipient in tablet and capsule formulations. Functions as a binder, filler, and disintegrant at concentrations of 5-15%.

Comments:

Pregelatinized starch improves tablet binding while maintaining disintegration properties. It enhances the mechanical strength of tablets and reduces friability.