Epitochem

Ferric Orthophosphate

Ferric orthophosphate is a yellow-white, odorless, tasteless powder consisting of iron(III) phosphate. It is sparingly soluble in water and commonly used in fortified foods and supplements due to its stability.

Chemical Name and CAS Registry Number: Iron(III) phosphate [10045-86-0]

Functional Category: Iron supplement; hematinic; nutrient fortifier

Pharmacopeial Specifications:

  • Iron Content: 28–32%

  • Identification: Positive for phosphate and iron

  • Loss on Ignition: 10–14%

  • Solubility: Practically insoluble in water

  • Microbial Limits: Complies with pharmacopeial standards

Applications in Pharmaceutical Formulation:

Primarily used in chewable tablets, capsules, and fortified food products for the treatment or prevention of iron deficiency. Its slow solubility makes it suitable for sustained-release formulations and food enrichment.

Comments:

Though less bioavailable than soluble iron salts, ferric orthophosphate is widely used in pediatric and food-grade applications due to its minimal taste impact and good stability. It is often preferred where high gastrointestinal tolerability is essential.