Epitochem

Microcrystalline Cellulose (MCC)

Microcrystalline Cellulose (MCC)
MCC

Microcrystalline Cellulose (MCC) is one of the most extensively used excipients across pharmaceutical, nutraceutical, food, and cosmetics industries. Recognized for its exceptional binding and diluting properties, MCC plays a vital role in the development of solid oral dosage forms.

Derived through the controlled hydrolysis of cellulose, MCC is known for its excellent compressibility, making it ideal for direct compression tablet manufacturing. MCC exhibits superior mechanical properties that promote tablet integrity while maintaining rapid disintegration.

CAS No: 9004-34-6
Functional Category: Adsorbent, suspending agent, tablet and capsule diluent; tablet disintegrant

Specification

Grade LOD (%) Bulk Density Application Packaging
MCC 105 1.0 – 5.0 0.20 – 0.30 Fine particle size enhances tablet disintegration, improving drug release & bioavailability. HDPE / Paper Bags
MCC 101 3.0 – 5.0 0.27 – 0.34 Versatile binder, diluent, and filler used in wet granulation and direct compression. HDPE / Paper Bags
MCC 103 1.0 – 3.0 0.26 – 0.34 Used as a binder, filler, and disintegrant in tablet and capsule formulations. HDPE / Paper Bags
MCC 301 3.0 – 5.0 0.34 – 0.45 Enhances drug adsorption & absorption in tablets, capsules, granules, and pellets. HDPE / Paper Bags
MCC 102 3.0 – 5.0 0.26 – 0.34 Binder, bulking agent, and disintegrant, commonly used in direct compression. HDPE / Paper Bags
MCC 112 0.0 – 1.5 0.26 – 0.34 Low moisture content grade, ideal for moisture-sensitive formulations. HDPE / Paper Bags
MCC 302 3.0 – 5.0 0.28 – 0.45 Used as a binder, filler, and disintegrant in tablets and capsules. HDPE / Paper Bags
MCC 12 3.0 – 5.0 0.26 – 0.40 Enhances compressibility, flowability, and drug content uniformity. HDPE / Paper Bags
MCC 112 3.0 – 5.0 0.31 – 0.39 Low moisture excipient for pharmaceutical & nutraceutical applications. HDPE / Paper Bags

FEATURES

Consistent Quality and Compliance

  • Pharmacopeial Compliance
  • Batch-to-Batch Consistency
  • Regulatory Certifications including ExciPact
  • Customizable Grades for Specific Applications

  • Offers a wide range of grades tailored to:
  • Direct compression
  • Wet or dry granulation
  • High-speed tableting
  • Low moisture or high-density formulations
  • Custom formulations or particle size
  • distribution to meet unique formulation challenges.
  • Versatile Functionality

    Acts as a binder, filler, flow aid, and disintegrant in both pharmaceutical and nutraceutical tablet and capsule formulations.

    Enhanced Blending Uniformity

    Its improved flow and reduced segregation make SMCC ideal for formulations with low-dose APIs or poor flow actives.